‘Ductal Carcinoma In Situ of the Breast’ – Is It Time to Replace This Term by ‘Ductal Intraepithelial Neoplasia of the Breast’?
نویسندگان
چکیده
منابع مشابه
'Ductal carcinoma in situ of the breast' -- is it time to replace this term by 'ductal intraepithelial neoplasia of the breast'?
sists, given the wide geographic variations in practice standards. This is especially true regarding the use of radiation therapy, in particular for patients with small, low-grade DCIS. The use of radiation therapy in these patients will interfere with any future uses of radiation therapy if and when they develop a true mammary carcinoma. On the other hand, if the designation of ‘carcinoma’ wer...
متن کاملDuctal Carcinoma In Situ of the Breast
PURPOSE The increasing incidence and biological heterogeneity of ductal carcinoma in situ (DCIS) of the breast have made the management of this entity challenging and controversial. This paper reviews data on the natural history of the disease and results obtained with various management approaches. DATA SOURCES Computerized MEDLINE search of articles related to DCIS published since 1966. S...
متن کاملDuctal Carcinoma In Situ of the Breast
Background: Ductal carcinoma in situ (DCIS) is detected more often since the advent of mammography. A standardized pathologic staging and grading system does not exist, but nuclear grade is assuming greater importance. The history of DCIS is long, and its treatment is a controversial issue in breast cancer today. Methods: Data have been reviewed regarding the role of HER-2 expression as a progn...
متن کاملBreast Ductal Carcinoma In Situ
Ductal carcinoma in situ (DCIS) of the breast is becoming one of the most important diseases diagnosed in preventive medicine screening. The current age-adjusted incidence rate of DCIS is 32.5 per 100,000 women. For women 50–64 years of age, the incidence is approximately 88 per 100,000. Currently, for every 4 diagnoses of invasive breast cancer, there is 1 diagnosis of DCIS. Risk of DCIS is ra...
متن کاملImmunohistochemical Evaluation of Human p53 Tumor Suppressor Protein Content in Ductal Carcinoma in Situ of the Breast
The focus of this study was to determine if early detection of mutant p53 accumulation may be an early indicator of tumor aggressiveness and transformation to invasive breast cancer. For this purpose, the p53 content of 100 human breast biopsies classified as ductal carcinoma (DCIS), was evaluated by immunohistochemical method. All specimens were microscopically classified into histologic types...
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ژورنال
عنوان ژورنال: Oncology Research and Treatment
سال: 2009
ISSN: 2296-5270,2296-5262
DOI: 10.1159/000207319